Nothing could reasonably prepare a football player, at any level, to play in the conditions that the Bills and Colts are playing in today. Visibility is almost nothing, any wide receiver running more than 20 yards down the field will be essentially impossible for a quarterback to see and that is even if a quarterback would be able to get enough of a grip on the ball to chuck it deep.
If you’re looking for creativity, you will be out of luck. The passing game will be reliant entirely on exploiting mismatches and will require risk taking.